Patterns in T-cell recognition
Exploring T-cell receptor function through mutational data and sequence-based models.
The question
What can a receptor’s sequence reveal about its function?
This work explores T-cell receptor function prediction using deep mutational scanning data. A related hackathon prototype examined classification from sequence data.
My contribution
- T Cell Receptor Function Prediction Model Based on Deep Mutational Scanning Datasets — Poster Presentation at Oxford University.
- Developed a CD4/CD8 TCR classify model based on sequence data.
- Completed prototype and delivered technical presentation comparing structure-based models.
Methods & tools
Sequence analysis · Deep mutational scanning · Model evaluation